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During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback, inhibited the release of pituitary luteinizing hormone (LH). In men, this suppresses endogenous hormone production and leads to the structural degeneration of the endocrine organs and glands, including the gonads. Over a very long period of time, humans have relied on various kinds of performance-enhancing substances.
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There is a fine line between too much or too little prednisone. But work in the early part of the 1900s indicated that exercise did not change protein needs and, until the 1970s, was accepted without further research. Anabolic steroids stimulate production of growth hormone (GH) which in turn stimulates the production of IGF-1.
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